Expresión de búsqueda: APC8 SUBUNIT, ANAPHASE-PROMOTING COMPLEX-CYCLOSOME 
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Descriptor Inglés:   Apc8 Subunit, Anaphase-Promoting Complex-Cyclosome 
Descriptor Español:   subunidad Apc8 del complejo promotor de la anafase-ciclosoma 
Descriptor Portugués:   Subunidade Apc8 do Ciclossomo-Complexo Promotor de Anáfase 
Sinónimos Inglés:   Anapc8
Apc8 Subunit, Anaphase-Promoting Complex
Apc8 Subunit, Anaphase Promoting Complex
Apc8 Subunit, Anaphase Promoting Complex Cyclosome  
Categoría:   D08.811.464.938.750.092.996
D12.776.167.024.996
Definición Inglés:   A highly conserved subunit of the anaphase-promoting complex (APC-C) containing multiple 34-amino-acid tetratricopeptide repeats. These domains, also found in Apc3, Apc6, and Apc7, have been shown to mediate protein-protein interactions, suggesting that Apc8 may assist in coordinating the juxtaposition of the catalytic and substrate recognition module subunits relative to coactivators and APC-C inhibitors. 
Nota Histórica Inglés:   2014 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número del Registro:   55282 
Identificador Único:   D064196 

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